Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5161931 | 0.98 | HSD17B10 (0.43) | HSD17B10PRKCIACHECYP1A2CYP3A4 | |
| SCHEMBL5164427 | 0.86 | POLB (0.46) | TDP1TSPOHRH3 | |
| SCHEMBL5161610 | 0.83 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2D6CYP2C19TDP1 | |
| SCHEMBL5159628 | 0.81 | CASP1 (0.36) | PRKCIACHECYP1A2CYP3A4TDP1 | |
| SCHEMBL5164492 | 0.81 | POLB (0.36) | PRKCITDP1MEN1KMT2ACA2 | |
| SCHEMBL5162901 | 0.78 | HDAC1 (0.35) | HSD17B10CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL29379067 | 0.78 | HSD17B10 (0.57) | HSD17B10CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL2131319 | 0.75 | LMNA (0.46) | HSD17B10CYP1A2CYP3A4HPGDTDP1 | |
| SCHEMBL5162267 | 0.74 | HSD17B10 (0.42) | HSD17B10CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL5491963 | 0.74 | CASP1 (0.50) | PRKCIACHECYP3A4TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007026312-A1 | 1,3-DIAMINOBENZENE DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |