⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3077020 | 0.79 | — | — | |
| SCHEMBL19092117 | 0.79 | — | — | |
| SCHEMBL2161386 | 0.69 | — | — | |
| SCHEMBL15766383 | 0.69 | ALOX5 (0.32) | — | |
| SCHEMBL6167946 | 0.69 | — | — | |
| SCHEMBL2386768 | 0.68 | — | — | |
| SCHEMBL813440 | 0.68 | — | — | |
| SCHEMBL29286884 | 0.67 | LMNA (0.47) | — | |
| SCHEMBL1696462 | 0.67 | LMNA (0.47) | — | |
| SCHEMBL11156754 | 0.67 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230280-B1 | Polymerizable composition | G C DENTAL IND CORP (JP) | 2013-09-18 | — | — | EP | claimed |
| EP-2182911-A2 | SELF-CURING SYSTEM FOR ENDODONTIC SEALANT APPLICATIONS | Pentron Clinical Technologies, LLC (US) | 2010-05-12 | — | — | EP | claimed |
| WO-2009018464-A2 | SELF-CURING SYSTEM FOR ENDODONTIC SEALANT APPLICATIONS | PENTRON CLINICAL TECHNOLOGIES, LLC (US) | 2009-02-05 | — | — | WO | claimed |
| US-20080003542-A1 | Self-Curing System For Endodontic Sealant Applications | PENTRON CLINICAL TECHNOLOGIES, LLC | 2008-01-03 | — | — | US | claimed |
| US-20030134933-A1 | Self-curing system for endodontic sealant applications | KERR CORPORATION | 2003-07-17 | — | — | US | claimed |
| EP-0554275-B1 | ACID BATH FOR COPPER PLATING, AND A PROCESS USING A BATH OF THIS TYPE FOR THIS PURPOSE | ATOTECH DEUTSCHLAND GMBH (DE) | 1994-12-14 | — | — | EP | claimed |
| EP-2981529-B1 | ORIDONIN ANALOGS, COMPOSITIONS, AND METHODS RELATED THERETO | UNIV TEXAS (US) | 2021-07-14 | — | — | EP | disclosed |
| US-10072022-B2 | Oridonin analogs, compositions, and methods related thereto | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-09-11 | — | — | US | disclosed |
| US-20170313716-A1 | ORIDONIN ANALOGS, COMPOSITIONS, AND METHODS RELATED THERETO | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2017-11-02 | — | — | US | disclosed |
| US-9725460-B2 | Oridonin analogs, compositions, and methods related thereto | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-08-08 | — | — | US | disclosed |
| US-20160096844-A1 | ORIDONIN ANALOGS, COMPOSITIONS, AND METHODS RELATED THERETO | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2016-04-07 | — | — | US | disclosed |
| EP-2981529-A1 | ORIDONIN ANALOGS, COMPOSITIONS, AND METHODS RELATED THERETO | The Board of Regents of The University of Texas System (US) | 2016-02-10 | — | — | EP | disclosed |
| WO-2014165841-A1 | ORIDONIN ANALOGS, COMPOSITIONS, AND METHODS RELATED THERETO | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-10-09 | — | — | WO | disclosed |
| US-20100093690-A1 | 5-PHENYLTHIAZOLE DERIVATIVES AND USE AS PI3 KINASE INHIBITORS | BRUCE IAN | 2010-04-15 | — | — | US | disclosed |
| US-7687637-B2 | 5-phenylthiazole derivatives and use as Pi3 kinase inhibitors | NOVARTIS AG (CH) | 2010-03-30 | — | — | US | disclosed |
| US-20080287364-A1 | Bitter Taste Receptors | BUFE BERND | 2008-11-20 | — | — | US | disclosed |
| US-20050119320-A1 | 5-phenylthiazole derivatives and use as pi3 kinase inhibitors | NOVARTIS AG (CH) | 2005-06-02 | — | — | US | disclosed |
| US-5705581-A | QUATERNARIUM ALKYL ACRYLAMIDES WITH FLUORIDE ION FOR DENTAL FILLINGS | INDIANA UNIVERSITY FOUNDATION (US) | 1998-01-06 | — | — | US | disclosed |
| US-5639840-A | METHACRYLIC ACID-BASED MONOMERS | INDIANA UNIVERSITY FOUNDATION (US) | 1997-06-17 | — | — | US | disclosed |
| WO-1996022761-A1 | FLUORIDE ION RELEASING DENTAL MATERIALS | INDIANA UNIVERSITY FOUNDATION (US) | 1996-08-01 | — | — | WO | disclosed |