Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.51 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 6/20 | 0.50 |
| ▸ | DHODH | Q02127 | 2/20 | 0.50 |
| ▸ | FYN | P06241 | 2/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | PAK4 | O96013 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2026663 | 0.93 | L3MBTL1 (0.52) | PARP1DHODHFYNCHEK2CDC7 | |
| SCHEMBL30903715 | 0.93 | L3MBTL1 (0.52) | PARP1DHODHFYNCHEK2CDC7 | |
| Hydrochloric Acid SCHEMBL28812686 | 0.91 | CHEK2 (0.50) | PARP1DHODHFYNCHEK2CDC7 | |
| SCHEMBL5307077 | 0.91 | PARP1 (0.56) | BAZ2BBAZ2APARP1DHODHFYN | |
| SCHEMBL3809549 | 0.86 | KMO (0.63) | POLBFNTAFNTBPGGT1BKMO | |
| SCHEMBL22289582 | 0.84 | CHEK2 (0.51) | DHODHCHEK2LCKMAPK1MAPT | |
| SCHEMBL8542133 | 0.83 | PDCD1 (0.49) | FYNCHEK2CDC7PLK4CHEK1 | |
| SCHEMBL43553 | 0.81 | DHODH (0.70) | PARP1DHODHFYNCHEK2CDC7 | |
| SCHEMBL29788172 | 0.81 | DHODH (0.70) | PARP1DHODHFYNCHEK2CDC7 | |
| SCHEMBL3937210 | 0.80 | PLAU (0.52) | PARP1CHEK2CSF1RFLT1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025575-A1 | O-HYDROXY- AND O-AMINO BENZAMIDE DERIVATIVES AS IKK2 INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-08 | — | — | WO | disclosed |