Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307157 | 1.00 | MAPT (0.49) | MAPTALDH1A1MEN1KMT2ACASP1 | |
| SCHEMBL14625355 | 0.86 | CYP3A4 (0.52) | MAPTALDH1A1KMT2ACASP1CYP3A4 | |
| SCHEMBL14625365 | 0.86 | CYP3A4 (0.48) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL14625714 | 0.84 | MAPT (0.48) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL14624818 | 0.83 | ALDH1A1 (0.45) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL5330894 | 0.83 | ALDH1A1 (0.49) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL5330899 | 0.83 | ALDH1A1 (0.49) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL5308650 | 0.82 | ALDH1A1 (0.50) | MAPTALDH1A1CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL5308646 | 0.82 | ALDH1A1 (0.50) | MAPTALDH1A1CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL14625121 | 0.80 | ALDH1A1 (0.45) | MAPTALDH1A1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011910-A2 | CHIRAL AMINE-CATALYZED ASYMMETRIC ADDITION OF CARBON-CENTERED NUCLEOPHILES TO IMINES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2007-01-25 | — | — | WO | disclosed |