Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164364 | 0.98 | GAA (0.36) | GAAEPHX2NR1H4KDM4ESMN1; SMN2 | |
| SCHEMBL5162503 | 0.89 | PTGS2 (0.36) | GAAPTGS2HPGDHTTHDAC3 | |
| Ammonia Solution, Strong SCHEMBL5307556 | 0.86 | L3MBTL1 (0.41) | GAAEPHX2NR1H4KDM4ESMN1; SMN2 | |
| SCHEMBL5165340 | 0.86 | CA12 (0.37) | GAAEPHX2NR1H4KDM4EHPGD | |
| SCHEMBL5162590 | 0.84 | L3MBTL1 (0.42) | GAAEPHX2NR1H4KDM4ESMN1; SMN2 | |
| SCHEMBL5163460 | 0.82 | HPGD (0.50) | KDM4ESMN1; SMN2HPGDALDH1A1HTT | |
| SCHEMBL5162095 | 0.81 | EPHX2 (0.39) | GAAEPHX2NR1H4KDM4EHPGD | |
| SCHEMBL5160950 | 0.81 | KDM4E (0.50) | GAAKDM4ESMN1; SMN2HPGDPOLB | |
| SCHEMBL14278969 | 0.79 | TAAR1 (0.42) | GAAKDM4ESMN1; SMN2HSD17B10HPGD | |
| SCHEMBL5164550 | 0.79 | ALDH1A1 (0.48) | GAAKDM4ESMN1; SMN2HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007026312-A1 | 1,3-DIAMINOBENZENE DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |