Iodide

Iodide

SCHEMBL5307270

CN(C)CCC(Oc1c(I)ccc2ccccc12)c1cccnc1.I

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 2/20 0.39
CACNA2D1 P54289 1/20 0.39
HRH1 P35367 4/20 0.39
CYP2D6 P10635 3/20 0.39
KCNH2 Q12809 2/20 0.39
CYP3A4 P08684 1/20 0.39
SLC6A4 P31645 2/20 0.36
HRH3 Q9Y5N1 1/20 0.36
UTS2R Q9UKP6 1/20 0.36
CYP51A1 Q16850 2/20 0.35
CHRNB2 P17787 1/20 0.34
CHRNA4 P43681 1/20 0.34
HTR2A P28223 1/20 0.33
CHRNA7 P36544 1/20 0.33
KCNA5 P22460 1/20 0.33
CHRM2 P08172 1/20 0.33
SLC6A2 P23975 1/20 0.33
SCN1A P35498 1/20 0.33
SCN2A Q99250 1/20 0.33
SCN3A Q9NY46 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL2607 0.82 CACNA2D1 (0.56) CACNA2D1SLC6A4SLC6A2
SCHEMBL5080333 0.81 CACNA2D1 (0.57) CACNA2D1SLC6A4SLC6A2
Oxalic Acid SCHEMBL3521 0.76 CACNA2D1 (0.52) CACNA2D1SLC6A4UTS2RSLC6A2
SCHEMBL5078645 0.69 SLC6A4 (0.51) SLC6A4HRH3CYP51A1CHRNB2CHRNA4
SCHEMBL9995405 0.67 SLC6A4 (0.67) CACNA2D1SLC6A4HRH3UTS2RSLC6A2
Bromide SCHEMBL6726247 0.66 SLC6A4 (0.65) CACNA2D1SLC6A4HRH3UTS2RSLC6A2
SCHEMBL11226530 0.65 SLC6A4 (0.49) HRH1CYP3A4SLC6A4HRH3HTR2A
Hydrochloric Acid SCHEMBL7771743 0.65 SLC6A4 (0.73) CACNA2D1SLC6A4SLC6A2
SCHEMBL30705397 0.64 CHRNA7 (0.49) HRH1CYP2D6CHRM1KCNH2CYP3A4
SCHEMBL11298123 0.64 CHRNA7 (0.49) HRH1CYP2D6CHRM1KCNH2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007041584-A2 IMPLANTABLE SENSORS, IMPLANTABLE PUMPS, AND ANTI-SCARRING DRUG COMBINATIONS COMBINATORX, INCORPORATED (US) 2007-04-12 WO disclosed