Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.58 |
| ▸ | HTR7 | P34969 | 5/20 | 0.58 |
| ▸ | HTR1A | P08908 | 4/20 | 0.58 |
| ▸ | HTR1D | P28221 | 4/20 | 0.58 |
| ▸ | HTR5A | P47898 | 4/20 | 0.58 |
| ▸ | HTR1E | P28566 | 3/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5308379 | 0.87 | HTR6 (0.58) | HTR6HTR7HTR1AHTR1DHTR5A | |
| SCHEMBL5313708 | 0.85 | HTR6 (0.67) | HTR6HTR7HTR1AHTR1DHTR5A | |
| SCHEMBL4656461 | 0.76 | HTR6 (0.70) | HTR6HTR7HTR1AHTR1DHTR5A | |
| SCHEMBL11817293 | 0.76 | HTR6 (0.63) | HTR6HTR7HTR1AHTR1DHTR5A | |
| SCHEMBL2537573 | 0.74 | HTR6 (1.00) | HTR6HTR7HTR1AHTR1DHTR5A | |
| SCHEMBL29389149 | 0.74 | HTR6 (1.00) | HTR6HTR7HTR1AHTR1DHTR5A | |
| SCHEMBL5308657 | 0.73 | HTR6 (0.46) | HTR6HTR7HTR1AHTR1DHTR5A | |
| SCHEMBL1817642 | 0.71 | HTR6 (1.00) | HTR6HTR7HTR1AHTR1DHTR5A | |
| SCHEMBL11810270 | 0.71 | HTR6 (0.52) | HTR6HTR7HTR1AHTR1DHTR2A | |
| SCHEMBL5766124 | 0.69 | HTR6 (1.00) | HTR6HTR7HTR1AHTR1DHTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | claimed |
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |