Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.46 |
| ▸ | HTR7 | P34969 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 4/20 | 0.46 |
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | HTR1D | P28221 | 3/20 | 0.46 |
| ▸ | HTR5A | P47898 | 3/20 | 0.46 |
| ▸ | HTR1E | P28566 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5308379 | 0.86 | HTR6 (0.58) | HTR6HTR7HTR2AHTR2CHTR1A | |
| SCHEMBL5313708 | 0.84 | HTR6 (0.67) | HTR6HTR7HTR2AHTR2CHTR1A | |
| SCHEMBL5313662 | 0.84 | TERT (0.38) | HTR6HTR7HTR2AHTR2CHTR1A | |
| SCHEMBL11811395 | 0.77 | GAA (0.45) | HTR6HTR7HTR2AHTR2CHTR1A | |
| SCHEMBL6823933 | 0.77 | HTR2A (0.72) | HTR6HTR7HTR2AHTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL5334181 | 0.76 | HTR6 (0.43) | HTR6HTR7HTR2AHTR2CHTR1A | |
| SCHEMBL5331577 | 0.76 | MPO (0.48) | HTR6MPOGAADRD2ALDH1A1 | |
| SCHEMBL11806316 | 0.75 | HTR6 (0.57) | HTR6HTR7HTR2AHTR2CHTR1A | |
| SCHEMBL11817293 | 0.75 | HTR6 (0.63) | HTR6HTR7HTR2AHTR2CHTR1A | |
| SCHEMBL5307688 | 0.73 | HTR6 (0.58) | HTR6HTR7HTR2AHTR2CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | claimed |
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |