Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.67 |
| ▸ | HTR1D | P28221 | 5/20 | 0.67 |
| ▸ | HTR1A | P08908 | 4/20 | 0.67 |
| ▸ | HTR7 | P34969 | 4/20 | 0.67 |
| ▸ | HTR5A | P47898 | 4/20 | 0.67 |
| ▸ | HTR2A | P28223 | 4/20 | 0.67 |
| ▸ | HTR1E | P28566 | 3/20 | 0.67 |
| ▸ | HTR2C | P28335 | 3/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR1F | P30939 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11817293 | 0.91 | HTR6 (0.63) | HTR6HTR1DHTR1AHTR7HTR5A | |
| SCHEMBL5307688 | 0.85 | HTR6 (0.58) | HTR6HTR1DHTR1AHTR7HTR5A | |
| SCHEMBL5308379 | 0.84 | HTR6 (0.58) | HTR6HTR1DHTR1AHTR7HTR5A | |
| SCHEMBL5308657 | 0.84 | HTR6 (0.46) | HTR6HTR1DHTR1AHTR7HTR5A | |
| SCHEMBL29389149 | 0.81 | HTR6 (1.00) | HTR6HTR1DHTR1AHTR7HTR5A | |
| SCHEMBL2537573 | 0.81 | HTR6 (1.00) | HTR6HTR1DHTR1AHTR7HTR5A | |
| SCHEMBL29423321 | 0.78 | HTR6 (1.00) | HTR6HTR1DHTR1AHTR7HTR5A | |
| SCHEMBL5763578 | 0.78 | HTR6 (1.00) | HTR6HTR1DHTR1AHTR7HTR5A | |
| SCHEMBL5329102 | 0.77 | KDM4E (0.46) | HTR6MTNR1AMTNR1BL3MBTL1KMT2A | |
| SCHEMBL5766124 | 0.76 | HTR6 (1.00) | HTR6HTR1DHTR1AHTR7HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | claimed |
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |