Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 18/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 16/20 | 0.44 |
| ▸ | CRACR2A | Q9BSW2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5226579 | 0.80 | ITGA4 (0.61) | ITGA4ITGB1 | |
| SCHEMBL5312486 | 0.78 | ITGB1 (0.49) | ITGA4ITGB1 | |
| SCHEMBL5309992 | 0.76 | ITGB1 (0.51) | ITGA4ITGB1 | |
| SCHEMBL5227315 | 0.71 | ITGB1 (0.56) | ITGA4ITGB1 | |
| SCHEMBL5255111 | 0.70 | P2RX7 (0.34) | — | |
| SCHEMBL5358246 | 0.70 | ITGB1 (0.64) | ITGA4ITGB1 | |
| SCHEMBL7261859 | 0.69 | ITGB1 (0.54) | ITGA4ITGB1 | |
| SCHEMBL5226968 | 0.67 | ITGB1 (0.67) | ITGA4ITGB1 | |
| SCHEMBL5256390 | 0.67 | ITGB1 (0.51) | ITGA4ITGB1 | |
| SCHEMBL5226501 | 0.67 | ITGA4 (0.66) | ITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622867-B1 | N-(2-PHENYLETHYL)SULFAMIDE DERIVATIVES AS INTEGRIN ALPHA4 ANTAGONISTS | ALMIRALL LAB (ES) | 2007-09-19 | — | — | EP | claimed |