Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 0.55 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | FABP2 | P12104 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5308792 | 0.87 | ELANE (0.57) | ELANEPPARGPPARAFABP2SLC22A12 | |
| SCHEMBL5281549 | 0.81 | ELANE (0.64) | ELANEPPARGPPARAFABP2SLC22A12 | |
| SCHEMBL18405594 | 0.80 | CA4 (0.39) | ELANEPPARGPPARAALDH1A1 | |
| SCHEMBL14139184 | 0.79 | ELANE (0.62) | ELANEALDH1A1STS | |
| SCHEMBL11441192 | 0.78 | PPARG (0.76) | ELANEPPARGPPARAFABP2SLC22A12 | |
| SCHEMBL5308750 | 0.78 | LTA4H (0.47) | PPARGPPARAALDH1A1 | |
| SCHEMBL29038424 | 0.77 | ELANE (0.49) | ELANEPPARGPPARAFABP2SLC22A12 | |
| SCHEMBL23544179 | 0.77 | ELANE (0.55) | ELANEPPARGPPARAFABP2SLC22A12 | |
| SCHEMBL22295633 | 0.77 | SRD5A2 (0.61) | ELANEPPARGPPARAFABP2SLC22A12 | |
| SCHEMBL27607343 | 0.77 | ELANE (0.58) | ELANEPPARGPPARAFABP2SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039609-A1 | PYRANODIBENZOFURAN DERIVATIVES WITH ANTIFUNGAL AND ANTIBACTERIAL ACTIVITY | INSTITUT PASTEUR (FR) | 2007-04-12 | — | — | WO | disclosed |
| EP-0355565-A1 | 6-Benzoyl-substituted 3,4-dihydro-2H-benzopyranes, method for their preparation and pharmaceutical preparations based on these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-28 | — | — | EP | disclosed |