Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | FABP2 | P12104 | 1/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21408547 | 0.88 | MEN1 (0.48) | ELANELMNAHPGDESR1ESR2 | |
| SCHEMBL5308495 | 0.87 | ELANE (0.55) | ELANEPPARGPPARAFABP2SLC22A12 | |
| SCHEMBL3418004 | 0.81 | ELANE (0.66) | ELANELMNAMAPTHTTHPGD | |
| SCHEMBL14139184 | 0.79 | ELANE (0.62) | ELANEMAPTMEN1KMT2AKDM4E | |
| SCHEMBL29038424 | 0.77 | ELANE (0.49) | ELANELMNAMAPTPPARGPPARA | |
| Fenofibrate Acid SCHEMBL22373737 | 0.77 | PPARG (0.73) | ELANELMNAMAPTHTTHPGD | |
| SCHEMBL7940897 | 0.74 | LMNA (0.58) | ELANELMNAMAPTHTTHPGD | |
| SCHEMBL5541822 | 0.74 | ESR1 (0.58) | ELANELMNAMAPTHTTHPGD | |
| SCHEMBL20076975 | 0.73 | ELANE (0.60) | ELANELMNAMAPTHPGDPPARG | |
| SCHEMBL4406876 | 0.73 | ELANE (1.00) | ELANELMNAMAPTHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039609-A1 | PYRANODIBENZOFURAN DERIVATIVES WITH ANTIFUNGAL AND ANTIBACTERIAL ACTIVITY | INSTITUT PASTEUR (FR) | 2007-04-12 | — | — | WO | disclosed |