Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14139184 | 0.79 | ELANE (0.62) | ELANEALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL5308792 | 0.77 | ELANE (0.57) | ELANELMNAMAPK1TDP1PPARA | |
| SCHEMBL5308495 | 0.77 | ELANE (0.55) | ELANEALDH1A1PPARAPPARGFABP2 | |
| SCHEMBL21408547 | 0.73 | MEN1 (0.48) | ELANEALDH1A1LMNAHSD17B10 | |
| SCHEMBL6432508 | 0.71 | GSTP1 (0.53) | HDAC3HDAC2HDAC8NPC1L3MBTL1 | |
| SCHEMBL2008822 | 0.71 | ELANE (0.56) | ELANEALDH1A1MAPK1RECQLTDP1 | |
| SCHEMBL505810 | 0.71 | HDAC3 (0.68) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL9196159 | 0.71 | ACHE (0.41) | ELANEALDH1A1LMNATDP1PPARA | |
| SCHEMBL29644892 | 0.71 | KMT2A (0.54) | ALDH1A1LMNARECQLHSD17B10TDP1 | |
| SCHEMBL7843630 | 0.70 | ELANE (0.39) | ELANEALDH1A1LMNAMAPK1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283936-A | Substituted amino ether-containing 2, 2-dimethyl benzopyran derivative and salt or solvate thereof, preparation and application thereof, and composition | 沈阳药科大学 | 2023-06-23 | — | — | CN | disclosed |