Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.55 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309082 | 0.88 | KDM5A (0.58) | KDM5AKDM5B | |
| SCHEMBL18584559 | 0.87 | KDM5A (0.57) | KDM5AKDM5BKDM4EALOX5 | |
| SCHEMBL4647482 | 0.86 | KDM5A (0.64) | KDM5AKDM5BKDM4E | |
| SCHEMBL14829907 | 0.80 | GABRA1 (0.53) | KDM5AKDM5BALOX5 | |
| SCHEMBL5330015 | 0.79 | KDM5A (0.64) | KDM5AKDM5BKDM4E | |
| SCHEMBL8142770 | 0.78 | KDM5A (0.62) | KDM5AKDM5B | |
| SCHEMBL4701132 | 0.75 | KDM5A (0.59) | KDM5AKDM5BKDM4EALOX5 | |
| SCHEMBL1058188 | 0.75 | KDM5A (0.68) | KDM5AKDM5BKDM4E | |
| SCHEMBL5334737 | 0.74 | KDM5A (0.58) | KDM5AKDM5BKDM4E | |
| SCHEMBL31422810 | 0.73 | KDM5A (0.57) | KDM5AKDM5BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |