Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.73 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.73 |
| ▸ | STK17B | O94768 | 3/20 | 0.62 |
| ▸ | TYR | P14679 | 3/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5308789 | 1.00 | RAB9A (0.73) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL10732937 | 0.89 | STK17B (0.63) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL10732939 | 0.89 | STK17B (0.63) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL10888508 | 0.88 | MAOA (0.60) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL10732569 | 0.88 | RAB9A (0.76) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL10889194 | 0.86 | RAB9A (0.56) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL5579527 | 0.85 | RAB9A (1.00) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL10889077 | 0.85 | RAB9A (0.64) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL10733193 | 0.85 | RAB9A (0.64) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL30509611 | 0.85 | APP (0.68) | RAB9AMEN1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |