Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.50 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25223880 | 0.82 | CYP3A4 (0.55) | CYP3A4DGAT2SLC16A3BAZ2BHPGDS | |
| SCHEMBL25213243 | 0.79 | MEN1 (0.49) | CYP3A4SLC16A3BAZ2BALDH1A1KDM4E | |
| SCHEMBL3593544 | 0.76 | ATR (0.63) | CYP3A4ATM | |
| SCHEMBL753759 | 0.76 | ALDH1A1 (0.59) | CYP3A4ALDH1A1KDM4EPOLBCYP1A2 | |
| SCHEMBL5100085 | 0.74 | EGLN1 (0.52) | ALDH1A1HPGD | |
| SCHEMBL5305431 | 0.74 | LDHA (0.49) | CYP3A4SLC16A3BAZ2BALDH1A1HPGD | |
| SCHEMBL2929188 | 0.73 | LDHA (0.56) | CYP3A4BAZ2BALDH1A1KDM4EHPGD | |
| SCHEMBL24993570 | 0.73 | ALDH1A1 (0.56) | CYP3A4DGAT2ALDH1A1KDM4EPOLB | |
| SCHEMBL306105 | 0.73 | SMN1; SMN2 (0.62) | ALDH1A1KDM4EHPGDL3MBTL1MEN1 | |
| SCHEMBL5270543 | 0.72 | P4HTM (0.64) | HIF1AALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034282-A2 | DIARYL-IMIDAZOLE COMPOUNDS CONDENSED WITH A HETEROCYCLE AS C3A RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |