SCHEMBL753759

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1874036	0.80	NPC1 (0.54)	ALDH1A1L3MBTL1POLBHPGDCYP1A2
	SCHEMBL6429451	0.79	NPC1 (0.55)	ALDH1A1L3MBTL1POLBHPGDCYP1A2
	SCHEMBL10603927	0.78	NPC1 (0.54)	ALDH1A1L3MBTL1POLBHPGDCYP1A2
	SCHEMBL10205813	0.78	L3MBTL1 (0.56)	ALDH1A1L3MBTL1POLBHPGDCYP1A2
	SCHEMBL3344444	0.77	NPC1 (0.59)	ALDH1A1L3MBTL1POLBHPGDCYP1A2
	SCHEMBL5235038	0.77	RAB9A (0.59)	ALDH1A1POLBHPGDCYP1A2CYP3A4
	SCHEMBL26048300	0.77	NPC1 (0.59)	ALDH1A1L3MBTL1POLBHPGDCYP1A2
	SCHEMBL17298873	0.77	NPC1 (0.52)	ALDH1A1L3MBTL1POLBHPGDCYP1A2
	SCHEMBL17052948	0.77	LMNA (0.55)	ALDH1A1L3MBTL1POLBHPGDCYP1A2
	SCHEMBL5309386	0.76	CYP3A4 (0.55)	ALDH1A1L3MBTL1POLBHPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.