Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5968252 | 0.86 | KDM4E (0.46) | KDM4ECHRM2CHRM5CHRM3ALDH1A1 | |
| SCHEMBL3985529 | 0.84 | KDM4E (0.47) | KDM4ECHRM2CHRM5CHRM3ALDH1A1 | |
| SCHEMBL18440963 | 0.81 | KDM4E (0.50) | KDM4ECHRM2CHRM5CHRM3ALDH1A1 | |
| SCHEMBL5308786 | 0.81 | THRB (0.62) | SMN1; SMN2L3MBTL1THRBATMHSD11B1 | |
| SCHEMBL5307775 | 0.80 | THRB (0.49) | SMN1; SMN2L3MBTL1THRBATMHSD11B1 | |
| SCHEMBL28203429 | 0.79 | ALDH1A1 (0.43) | KDM4ECHRM2CHRM5CHRM3ALDH1A1 | |
| SCHEMBL23640028 | 0.78 | EPHX2 (0.46) | KDM4ECHRM2CHRM5CHRM3ALDH1A1 | |
| SCHEMBL4877080 | 0.78 | KDM4E (0.45) | KDM4ECHRM2CHRM5CHRM3ALDH1A1 | |
| SCHEMBL1087862 | 0.78 | EPHX1 (0.55) | KDM4ECHRM2CHRM5CHRM3ALDH1A1 | |
| SCHEMBL3333281 | 0.76 | SMN1; SMN2 (0.61) | KDM4ECHRM2CHRM5CHRM3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007016610-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-02-08 | — | — | WO | disclosed |