Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307775 | 0.89 | THRB (0.49) | THRBATML3MBTL1RAB9AHSD11B1 | |
| SCHEMBL704010 | 0.84 | RAB9A (0.51) | THRBATML3MBTL1RAB9AHSD11B1 | |
| SCHEMBL5968252 | 0.83 | KDM4E (0.46) | THRBATML3MBTL1RAB9AHSD11B1 | |
| SCHEMBL2321238 | 0.83 | KMT2A (0.49) | THRBATML3MBTL1RAB9AHSD11B1 | |
| SCHEMBL4079112 | 0.83 | THRB (0.51) | THRBATML3MBTL1RAB9AHSD11B1 | |
| SCHEMBL794087 | 0.83 | RAB9A (0.50) | THRBATML3MBTL1RAB9AHSD11B1 | |
| SCHEMBL8262844 | 0.83 | RAB9A (0.50) | THRBATML3MBTL1RAB9AHSD11B1 | |
| SCHEMBL793658 | 0.81 | RAB9A (0.49) | THRBATML3MBTL1RAB9AHSD11B1 | |
| SCHEMBL4633597 | 0.81 | RAB9A (0.49) | THRBATML3MBTL1RAB9AHSD11B1 | |
| SCHEMBL4632551 | 0.81 | RAB9A (0.49) | THRBATML3MBTL1RAB9AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007016610-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-02-08 | — | — | WO | disclosed |