Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTGFR | P43088 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003157 | 0.86 | CYP2C19 (0.64) | PDE4BALDH1A1SMN1; SMN2PKMCYP2C19 | |
| SCHEMBL17045908 | 0.84 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2PKMPOLBGAA | |
| SCHEMBL17045933 | 0.82 | HDAC1 (0.59) | ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL530937 | 0.80 | IDO1 (0.47) | ALDH1A1SMN1; SMN2PKMGAA | |
| SCHEMBL13067926 | 0.80 | IDO1 (0.47) | ALDH1A1SMN1; SMN2PKMGAA | |
| SCHEMBL5180355 | 0.80 | CYP2C19 (0.54) | ALDH1A1SMN1; SMN2PKMCYP2C19FFAR1 | |
| SCHEMBL3938443 | 0.80 | CYP2C19 (0.73) | ALDH1A1SMN1; SMN2LTB4RCYP2C19FFAR1 | |
| SCHEMBL1585162 | 0.80 | CYP2C19 (0.73) | ALDH1A1SMN1; SMN2LTB4RCYP2C19FFAR1 | |
| SCHEMBL19756295 | 0.79 | ALDH1A1 (0.50) | PDE4BALDH1A1CYP2C19PLA2G4BPOLB | |
| SCHEMBL9663959 | 0.79 | LTB4R (0.69) | PDE4BLTB4RFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1610126-B1 | A system for determining the electrical potential across a membrane | UNIV CALIFORNIA (US) | 2014-04-30 | — | — | EP | disclosed |
| EP-1409456-B1 | DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS | UNIV CALIFORNIA (US) | 2012-02-08 | — | — | EP | disclosed |
| EP-0977035-B2 | A system for determining the electrical potential across a membrane | UNIV CALIFORNIA (US) | 2010-07-21 | — | — | EP | disclosed |
| US-7687282-B2 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-03-30 | — | — | US | disclosed |
| US-7173130-B2 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-02-06 | — | — | US | disclosed |
| US-20070026384-A1 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-02-01 | — | — | US | disclosed |
| US-7118899-B2 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-10-10 | — | — | US | disclosed |
| US-7115401-B2 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-10-03 | — | — | US | disclosed |
| US-7087416-B2 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-08-08 | — | — | US | disclosed |
| EP-1610126-A1 | A system for determining the electrical potential across a membrane | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-12-28 | — | — | EP | disclosed |
| US-6596522-B2 | Compositions and optical methods for determining transmembrane potentials across plasma membrane of biological cells | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-07-22 | — | — | US | disclosed |
| US-20030129670-A1 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-07-10 | — | — | US | disclosed |
| US-20020164577-A1 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-11-07 | — | — | US | disclosed |
| US-20020137201-A1 | DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-09-26 | — | — | US | disclosed |
| US-6342379-B1 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-01-29 | — | — | US | disclosed |
| US-6107066-A | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0977035-A2 | A system for determining the electrical potential across a membrane | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0834074-B1 | DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS | UNIV CALIFORNIA (US) | 1999-11-03 | — | — | EP | disclosed |
| EP-0834074-A1 | DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996041166-A2 | DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070026384-A1 | Detection of transmembrane potentials by optical methods | MBOAT1, TRPM4, NME4 | PDE4B 1821/4885ALDH1A1 2425/4885SMN1; SMN2 4297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.