Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 3/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11093662 | 0.91 | FFAR3 (0.39) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetone SCHEMBL28492790 | 0.90 | ALDH1A1 (0.43) | FFAR3LCKFYNALDH1A1TSHR | |
| Succinic Acid SCHEMBL5309775 | 0.89 | LMNA (0.50) | FFAR3ALDH1A1TSHRTDP1HDAC3 | |
| Acetic Acid SCHEMBL27509837 | 0.87 | FFAR3 (0.47) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL2160566 | 0.87 | FFAR3 (0.47) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL10531259 | 0.87 | FFAR3 (0.47) | FFAR3LCKFYNALDH1A1TSHR | |
| Alcohol SCHEMBL1052547 | 0.86 | — | — | |
| Acetic Acid SCHEMBL3359645 | 0.86 | FFAR3 (0.64) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL15090782 | 0.86 | FFAR3 (0.64) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL10680248 | 0.86 | FFAR3 (0.64) | FFAR3LCKFYNALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007035589-A1 | MINIMAL GROWTH MEDIUM FOR ACTINOBACILLUS SUCCINOGENES | MICHIGAN STATE UNIVERSITY (US) | 2007-03-29 | — | — | WO | disclosed |
| CN-1876050-A | Pharmaceutical preparation for treating prostatitis, its preparation process and quality control method | GUIYANG YUNYAN XICHUANG PHARM (CN) | 2006-12-13 | — | — | CN | disclosed |