Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 7/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 4/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.37 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311328 | 0.93 | LCK (0.43) | LCKKDRHCAR1HCAR2GHSR | |
| SCHEMBL5311465 | 0.91 | KDR (0.46) | LCKKDRTBK1 | |
| SCHEMBL5315703 | 0.87 | LCK (0.40) | LCKKDRFGFR1EPHB4TYK2 | |
| SCHEMBL5312796 | 0.87 | LCK (0.40) | LCKKDR | |
| SCHEMBL14531020 | 0.84 | LCK (0.49) | LCKCHEK1KDRSIK2SIK3 | |
| SCHEMBL5310105 | 0.83 | KDR (0.46) | LCKKDRTBK1 | |
| SCHEMBL14530838 | 0.81 | KDR (0.48) | LCKCHEK1KDRSIK2SIK3 | |
| SCHEMBL5312762 | 0.80 | LCK (0.45) | LCKCHEK1KDRTBK1 | |
| SCHEMBL5315162 | 0.79 | KDR (0.51) | LCKKDRTBK1 | |
| SCHEMBL5312683 | 0.79 | LCK (0.39) | LCKKDRFGFR1EPHB4TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |