Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.42 |
| ▸ | FABP1 | P07148 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313553 | 1.00 | SRD5A2 (0.49) | SRD5A2FFAR1SMN1; SMN2FFAR4PPARD | |
| SCHEMBL5310252 | 0.92 | FFAR1 (0.47) | SRD5A2FFAR1SMN1; SMN2PPARDAKR1C3 | |
| SCHEMBL5310255 | 0.92 | FFAR1 (0.47) | SRD5A2FFAR1SMN1; SMN2PPARDAKR1C3 | |
| SCHEMBL5335188 | 0.90 | FFAR1 (0.43) | SRD5A2FFAR1AKR1C3PLA2G4BFABP1 | |
| SCHEMBL5335192 | 0.90 | FFAR1 (0.43) | SRD5A2FFAR1AKR1C3PLA2G4BFABP1 | |
| SCHEMBL5315649 | 0.88 | LMNA (0.44) | SRD5A2FFAR1AKR1C3NPC1 | |
| SCHEMBL5315653 | 0.88 | LMNA (0.44) | SRD5A2FFAR1AKR1C3NPC1 | |
| SCHEMBL5313544 | 0.85 | FFAR1 (0.42) | SRD5A2FFAR1SMN1; SMN2AKR1C3FABP1 | |
| SCHEMBL5313546 | 0.85 | FFAR1 (0.42) | SRD5A2FFAR1SMN1; SMN2AKR1C3FABP1 | |
| SCHEMBL5315624 | 0.84 | L3MBTL1 (0.43) | SMN1; SMN2AKR1C3NPC1POLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |