SCHEMBL5310282

SCHEMBL5310282

O=C(O)c1ccccc1C(=O)c1cccc(F)c1F

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.59
CES1 P23141 3/20 0.59
BCHE P06276 1/20 0.59
ALB P02768 1/20 0.55
CDC25B P30305 3/20 0.55
ALDH1A1 P00352 2/20 0.54
ALOX15 P16050 2/20 0.54
AKR1C3 P42330 3/20 0.53
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
KMT2A Q03164 1/20 0.51
PRNP P04156 1/20 0.50
CDC25A P30304 1/20 0.47
HSD17B10 Q99714 1/20 0.47
ATM Q13315 1/20 0.47
KAT6A Q92794 1/20 0.46
POLB P06746 1/20 0.46
HPGD P15428 1/20 0.46
NR4A1 P22736 1/20 0.46
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3440833 0.88 CES2 (0.74) CES2CES1BCHEALBALDH1A1
SCHEMBL9178259 0.86 ALDH1A1 (0.61) CES2CES1ALBCDC25BALDH1A1
SCHEMBL5613020 0.86 CES2 (0.65) CES2CES1BCHEALBALDH1A1
SCHEMBL365453 0.86 CES2 (0.71) CES2CES1BCHEALBALDH1A1
SCHEMBL19244788 0.84 CES2 (0.53) CES2CES1BCHECDC25BALDH1A1
Fluoride SCHEMBL6441128 0.84 CES2 (0.68) CES2CES1BCHEALBALDH1A1
SCHEMBL27805264 0.84 CES2 (0.68) CES2CES1BCHEALBALDH1A1
Hydrochloric Acid SCHEMBL3199889 0.84 CES2 (0.68) CES2CES1BCHEALBALDH1A1
Hydrochloric Acid SCHEMBL31609616 0.84 CES2 (0.68) CES2CES1BCHEALBALDH1A1
SCHEMBL28157809 0.84 CES2 (0.68) CES2CES1BCHEALBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007044184-A1 WATER SOLUBLE PHOTOINITIATOR ALBEMARLE CORPORATION (US) 2007-04-19 WO disclosed