Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.60 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16920963 | 0.82 | MGAM (0.47) | KMT2AMAPTHPGDNPC1RAB9A | |
| SCHEMBL13058923 | 0.80 | KMT2A (0.43) | KMT2AL3MBTL1HTR6MAPTHPGD | |
| SCHEMBL10939923 | 0.79 | KMT2A (0.65) | KMT2AL3MBTL1HTR6MAPTHPGD | |
| SCHEMBL5310796 | 0.79 | L3MBTL1 (0.56) | KMT2AL3MBTL1MAPTHPGDNPC1 | |
| SCHEMBL16920959 | 0.78 | HSD17B10 (0.65) | KMT2AL3MBTL1MAPTHPGDNPC1 | |
| SCHEMBL13058925 | 0.77 | NPSR1 (0.48) | KMT2AL3MBTL1HTR6MAPTRAB9A | |
| SCHEMBL5314567 | 0.77 | HPGD (0.60) | KMT2AL3MBTL1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL862001 | 0.76 | L3MBTL1 (0.40) | KMT2AL3MBTL1HTR6MAPTHPGD | |
| SCHEMBL5309815 | 0.75 | KMT2A (0.55) | KMT2AL3MBTL1HTR6MAPTHPGD | |
| SCHEMBL13058922 | 0.75 | MAPT (0.44) | KMT2AMAPTHPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007048064-A2 | AMINO-PYRIMIDINES AS CASEIN KINASE II (CK2) MODULATORS | EXELIXIS, INC. (US) | 2007-04-26 | — | — | WO | disclosed |