Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 6/20 | 0.53 |
| ▸ | MGAM | O43451 | 3/20 | 0.53 |
| ▸ | SI | P14410 | 3/20 | 0.53 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314567 | 0.85 | HPGD (0.60) | L3MBTL1MAPTKMT2AGAAMGAM | |
| SCHEMBL14133162 | 0.83 | GAA (0.66) | L3MBTL1MAPTKMT2AGAAMGAM | |
| SCHEMBL5311182 | 0.83 | L3MBTL1 (0.51) | L3MBTL1MAPTKMT2AGAAMGAM | |
| SCHEMBL5310110 | 0.82 | L3MBTL1 (0.51) | L3MBTL1MAPTKMT2AGAAMGAM | |
| SCHEMBL5309782 | 0.82 | HPGD (0.67) | L3MBTL1KMT2AGAAMGAMSI | |
| SCHEMBL5310114 | 0.81 | HPGD (0.57) | L3MBTL1MAPTKMT2AGAAMGAM | |
| SCHEMBL5310304 | 0.79 | KMT2A (0.69) | L3MBTL1MAPTKMT2AGAAMGAM | |
| SCHEMBL489580 | 0.78 | CXCR2 (0.50) | L3MBTL1MAPTKMT2AGAAMGAM | |
| SCHEMBL21338153 | 0.76 | HPGD (0.71) | L3MBTL1KMT2AGAAMGAMSI | |
| SCHEMBL490197 | 0.74 | CXCR2 (0.49) | MAPTKMT2AGAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007048064-A2 | AMINO-PYRIMIDINES AS CASEIN KINASE II (CK2) MODULATORS | EXELIXIS, INC. (US) | 2007-04-26 | — | — | WO | disclosed |