Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | MGAM | O43451 | 3/20 | 0.51 |
| ▸ | SI | P14410 | 3/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21338153 | 0.90 | HPGD (0.71) | HPGDTSHRL3MBTL1KMT2AGAA | |
| SCHEMBL5310796 | 0.85 | L3MBTL1 (0.56) | HPGDTSHRL3MBTL1MAPTKMT2A | |
| SCHEMBL5309782 | 0.85 | HPGD (0.67) | HPGDTSHRL3MBTL1KMT2AGAA | |
| SCHEMBL16920967 | 0.85 | SMN1; SMN2 (0.52) | HPGDTSHRL3MBTL1MAPTKMT2A | |
| SCHEMBL16998639 | 0.84 | HPGD (0.44) | HPGDTSHRL3MBTL1MAPTKMT2A | |
| SCHEMBL843307 | 0.84 | NPSR1 (0.47) | HPGDTSHRL3MBTL1MAPTKMT2A | |
| SCHEMBL13067210 | 0.84 | NPSR1 (0.59) | HPGDTSHRL3MBTL1MAPTKMT2A | |
| SCHEMBL16998677 | 0.84 | NPSR1 (0.47) | HPGDTSHRL3MBTL1MAPTKMT2A | |
| SCHEMBL843977 | 0.84 | HPGD (0.44) | HPGDTSHRL3MBTL1MAPTKMT2A | |
| SCHEMBL843456 | 0.84 | MEN1 (0.66) | HPGDTSHRL3MBTL1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432776-B1 | METHYL SULFANYL PYRIMIDINES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS | UNIV LAVAL (CA) | 2019-09-11 | — | — | EP | disclosed |
| US-9510593-B2 | S-benzylthiouracil compounds and methods of enhancing plant root growth | VALENT BIOSCIENCES CORPORATION (US) | 2016-12-06 | — | — | US | disclosed |
| US-9510593-B2 | S-benzylthiouracil compounds and methods of enhancing plant root growth | VALENT BIOSCIENCES CORPORATION (US) | 2016-12-06 | — | — | US | disclosed |
| US-9315521-B2 | Pyrimidines as novel therapeutic agents | UNIVERSITé LAVAL (CA) | 2016-04-19 | — | — | US | disclosed |
| US-9315521-B2 | Pyrimidines as novel therapeutic agents | UNIVERSITé LAVAL (CA) | 2016-04-19 | — | — | US | disclosed |
| US-20150225423-A1 | PYRIMIDINES AS NOVEL THERAPEUTIC AGENTS | UNIVERSITé LAVAL (CA) | 2015-08-13 | — | — | US | disclosed |
| US-20150225423-A1 | PYRIMIDINES AS NOVEL THERAPEUTIC AGENTS | UNIVERSITé LAVAL (CA) | 2015-08-13 | — | — | US | disclosed |
| US-20150201620-A1 | S-BENZYLTHIOURACIL COMPOUNDS AND METHODS OF ENHANCING PLANT ROOT GROWTH | VALENT BIOSCIENCES LLC | 2015-07-23 | — | — | US | disclosed |
| US-20150201620-A1 | S-BENZYLTHIOURACIL COMPOUNDS AND METHODS OF ENHANCING PLANT ROOT GROWTH | VALENT BIOSCIENCES LLC | 2015-07-23 | — | — | US | disclosed |
| WO-2015108938-A1 | S-BENZYLTHIOURACIL COMPOUNDS AND METHODS OF ENHANCING PLANT ROOT GROWTH | VALENT BIOSCIENCES CORPORATION (US) | 2015-07-23 | — | — | WO | disclosed |
| US-9040538-B2 | Pyrimidines as novel therapeutic agents | UNIVERSITE LAVAL (CA) | 2015-05-26 | — | — | US | disclosed |
| US-20100298336-A1 | PYRIMIDINES AS NOVEL THERAPEUTIC AGENTS | UNIVERSITE LAVAL (CA) | 2010-11-25 | — | — | US | disclosed |
| WO-2010132999-A1 | METHYL SULFANYL PYRMIDMES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS | CHLORION PHARMA, INC. (CA) | 2010-11-25 | — | — | WO | disclosed |
| WO-2007048064-A2 | AMINO-PYRIMIDINES AS CASEIN KINASE II (CK2) MODULATORS | EXELIXIS, INC. (US) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298336-A1 | PYRIMIDINES AS NOVEL THERAPEUTIC AGENTS | TYMS, P2RX2, TYMP | HPGD 342/4885TSHR 4661/4885L3MBTL1 4706/4885 |
| US-20150201620-A1 | S-BENZYLTHIOURACIL COMPOUNDS AND METHODS OF ENHANCING PLANT ROOT GROWTH | SRM, TST, BROX | HPGD 2965/4885TSHR 57/4885L3MBTL1 1817/4885 |
| US-20150225423-A1 | PYRIMIDINES AS NOVEL THERAPEUTIC AGENTS | TYMS, P2RX2, TYMP | HPGD 342/4885TSHR 4661/4885L3MBTL1 4706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.