Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GALR2 | O43603 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2933889 | 0.84 | HTT (0.56) | HTTALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL3030037 | 0.82 | LMNA (0.60) | HTTALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL13987767 | 0.81 | KMT2A (0.53) | HTTALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL27303263 | 0.81 | HTT (0.59) | HTTALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL30483195 | 0.80 | ALDH1A1 (0.72) | HTTALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL3164500 | 0.80 | ALDH1A1 (0.66) | HTTALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL7600834 | 0.80 | ALDH1A1 (0.72) | HTTALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL988312 | 0.79 | LMNA (0.50) | HTTMAPTTDP1SMN1; SMN2CYP1A2 | |
| SCHEMBL11526803 | 0.76 | HTT (0.71) | HTTALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL27601335 | 0.75 | MAPT (0.79) | HTTALDH1A1MAPTTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034282-A2 | DIARYL-IMIDAZOLE COMPOUNDS CONDENSED WITH A HETEROCYCLE AS C3A RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |