Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 7/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GALR2 | O43603 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988797 | 0.89 | LMNA (0.44) | HTTALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL988796 | 0.89 | LMNA (0.44) | HTTALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL8423468 | 0.84 | GPR35 (0.54) | HTTALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL5310380 | 0.84 | HTT (0.55) | HTTALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL988023 | 0.81 | ALDH1A1 (0.60) | HTTALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL29674877 | 0.79 | HTT (0.66) | HTTALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL3911774 | 0.79 | HTT (0.66) | HTTALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL4271625 | 0.79 | HTT (0.61) | HTTALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL13987767 | 0.79 | KMT2A (0.53) | HTTALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL27303263 | 0.78 | HTT (0.59) | HTTALDH1A1MAPTTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |