Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5661801 | 0.93 | LTA4H (0.61) | LTA4HDRD2 | |
| SCHEMBL5659684 | 0.93 | LTA4H (0.61) | LTA4HDRD2 | |
| SCHEMBL3032189 | 0.83 | LTA4H (0.78) | LTA4H | |
| SCHEMBL5310458 | 0.83 | LTA4H (1.00) | LTA4H | |
| SCHEMBL3039708 | 0.77 | LTA4H (0.69) | LTA4H | |
| SCHEMBL3030590 | 0.77 | LTA4H (0.65) | LTA4H | |
| SCHEMBL5311202 | 0.77 | LTA4H (0.84) | LTA4H | |
| SCHEMBL3039091 | 0.76 | LTA4H (0.67) | LTA4H | |
| SCHEMBL3037434 | 0.76 | LTA4H (0.66) | LTA4H | |
| SCHEMBL3033373 | 0.76 | LTA4H (0.67) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079003-A2 | AMIDE INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-07-12 | — | — | WO | disclosed |
| US-20070155727-A1 | Amide inhibitors of leukotriene A4 hydrolase | SCHERING AKTIENGESSELLSCHAFT (DE) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155727-A1 | Amide inhibitors of leukotriene A4 hydrolase | LTA4H, LTB4R, LTC4S | LTA4H 1/4885DRD2 2126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.