Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311525 | 0.86 | ALDH1A1 (0.76) | ALDH1A1GAASMN1; SMN2MAPTLMNA | |
| SCHEMBL5314276 | 0.86 | ALDH1A1 (0.76) | ALDH1A1GAASMN1; SMN2MAPTLMNA | |
| SCHEMBL5311632 | 0.81 | ALDH1A1 (0.61) | ALDH1A1GAAMEN1KMT2ARAB9A | |
| SCHEMBL5311963 | 0.80 | ALDH1A1 (0.57) | ALDH1A1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13211115 | 0.78 | ENPP2 (0.45) | ALDH1A1ALDH3A1MEN1KMT2AAGTR1 | |
| SCHEMBL27462797 | 0.77 | ALDH1A1 (0.47) | ALDH1A1GAASMN1; SMN2MAPTCTSL | |
| SCHEMBL5314490 | 0.74 | ALDH1A1 (0.74) | ALDH1A1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL5311098 | 0.74 | ALDH1A1 (0.74) | ALDH1A1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL30731679 | 0.72 | ALDH1A1 (1.00) | ALDH1A1GAAMEN1KMT2ARAB9A | |
| SCHEMBL5311694 | 0.72 | CA2 (0.58) | ALDH1A1GAAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799823-B1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | DAIICHI SANKYO CO LTD (JP) | 2007-10-31 | — | — | EP | disclosed |
| US-RE39420-E1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | SANKYO COMPANY, LIMITED (JP) | 2006-12-05 | — | — | US | disclosed |
| CN-1151126-C | 1, 2-diphenylpyrrole derivatives, their preparation and their therapeutic uses | ������������ʽ���� | 2004-05-26 | — | — | CN | disclosed |
| US-5908858-A | OSTEOPOROSIS; LEUKOTRIENE INHIBITOR | SANKYO COMPANY, LIMITED (JP) | 1999-06-01 | — | — | US | disclosed |
| CN-1168372-A | 1, 2-diphenylpyrrole derivatives, their preparation and their therapeutic uses | SANKYO CO (JP) | 1997-12-24 | — | — | CN | disclosed |
| EP-0799823-A1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1997-10-08 | — | — | EP | disclosed |