Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2954867 | 0.92 | KDM4E (0.42) | KDM4EMAPK1NPSR1ROCK2LMNA | |
| SCHEMBL2946799 | 0.88 | LMNA (0.43) | KDM4EMAPK1NPSR1LMNAEGFR | |
| SCHEMBL5749051 | 0.81 | KDM4E (0.42) | KDM4EMAPK1NPSR1ROCK2LMNA | |
| SCHEMBL27632916 | 0.80 | KDM4E (0.41) | KDM4EMAPK1NPSR1ROCK2LMNA | |
| SCHEMBL591501 | 0.79 | ALDH1A1 (0.45) | KDM4EMAPK1NPSR1LMNAGABRA1 | |
| SCHEMBL3831839 | 0.79 | PDE2A (0.30) | — | |
| SCHEMBL3243876 | 0.76 | SRC (0.43) | KDM4EMAPK1NPSR1ROCK2LMNA | |
| SCHEMBL5747019 | 0.73 | PARP1 (0.40) | LMNAALDH1A1MAPTHTTTP53 | |
| SCHEMBL3273397 | 0.73 | MAP2K1 (0.52) | KDM4ENPSR1EGFRMAPTL3MBTL1 | |
| SCHEMBL4849696 | 0.73 | KCNH2 (0.41) | KDM4EMAPK1NPSR1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007016610-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-02-08 | — | — | WO | disclosed |