Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6519432 | 0.91 | FAAH (0.39) | THRBTSHRDGKAFAAHNAAA | |
| SCHEMBL6515076 | 0.91 | DGKA (0.38) | THRBTSHRDGKAFAAHNAAA | |
| SCHEMBL194857 | 0.90 | TSHR (0.52) | TSHRDGKAFAAHNAAAALDH1A1 | |
| SCHEMBL28132099 | 0.88 | TSHR (0.50) | TSHRDGKAFAAHNAAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL10881989 | 0.88 | TSHR (0.50) | TSHRDGKAFAAHNAAAALDH1A1 | |
| SCHEMBL6520524 | 0.87 | FAAH (0.46) | THRBTSHRDGKAFAAHNAAA | |
| SCHEMBL9056866 | 0.87 | THRB (0.43) | THRBTSHRDGKACYP3A4ALDH1A1 | |
| SCHEMBL15156040 | 0.86 | TSHR (0.58) | TSHRDGKAFAAHNAAAALDH1A1 | |
| SCHEMBL28117884 | 0.86 | TSHR (0.58) | TSHRDGKAFAAHNAAAALDH1A1 | |
| SCHEMBL23306689 | 0.86 | TSHR (0.50) | THRBTSHRDGKAFAAHNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8277372-A | — | — | None | — | — | JP | disclosed |
| JP-H08277372-A | COATING COMPOSITION | NIPPON OIL & FATS CO LTD | 1996-10-22 | — | — | JP | disclosed |
| US-4463149-A | UNSATURATED POLYSILOXANES | POLYMER TECHNOLOGY CORPORATION (US) | 1984-07-31 | — | — | US | disclosed |