Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4490436 | 0.75 | POLB (0.32) | PTGS2 | |
| SCHEMBL27989702 | 0.64 | BRD4 (0.32) | — | |
| SCHEMBL27411171 | 0.64 | CRBN (0.50) | — | |
| SCHEMBL21846831 | 0.63 | CRBN (0.34) | — | |
| SCHEMBL23028988 | 0.61 | POLB (0.32) | — | |
| SCHEMBL17818472 | 0.57 | SLC6A4 (0.46) | — | |
| SCHEMBL17014807 | 0.57 | PTGS2 (0.38) | PTGS2 | |
| SCHEMBL23029068 | 0.57 | — | — | |
| SCHEMBL19377760 | 0.57 | GSK3B (0.46) | — | |
| SCHEMBL12128675 | 0.55 | ADORA2B (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070231260-A1 | Transporter-targeted methods of diagnosis and treatment | XENOPORT, INC. (US) | 2007-10-04 | — | — | US | disclosed |
| WO-2007041268-A2 | TRANSPORTER-TARGETED METHODS OF DIAGNOSIS AND TREATMENT | XENOPORT, INC. (US) | 2007-04-12 | — | — | WO | disclosed |