Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CHAT | P28329 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | ALPG | P10696 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11398927 | 1.00 | CYP2A6 (0.47) | CYP2A6TERTRAB9AALDH1A1KDM4E | |
| SCHEMBL7047125 | 0.94 | CYP2A6 (0.48) | CYP2A6TERTRAB9AKDM4ECYP2C19 | |
| SCHEMBL4688796 | 0.87 | TERT (0.43) | TERTRAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL372527 | 0.87 | CHAT (0.61) | TERTRAB9AALDH1A1KDM4ECHAT | |
| Sulfuric Acid SCHEMBL7787999 | 0.86 | CHAT (0.52) | CYP2A6RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL9777588 | 0.85 | CYP2A6 (0.43) | CYP2A6ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL531126 | 0.85 | MEN1 (0.63) | TERTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL531127 | 0.85 | MEN1 (0.63) | TERTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL10968004 | 0.84 | TERT (0.46) | TERTRAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL6318506 | 0.84 | MEN1 (0.47) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| US-20190091492-A1 | PHOTO-CURABLE COSMETIC COMPOSITIONS | L'OREAL (FR) | 2019-03-28 | — | — | US | disclosed |
| US-8609074-B2 | Methods for making up a keratinous substrate | L'OREAL (FR) | 2013-12-17 | — | — | US | disclosed |
| US-20130167859-A1 | METHODS FOR MAKING UP A KERATINOUS SUBSTRATE | L'OREAL S.A. (FR) | 2013-07-04 | — | — | US | disclosed |
| US-20130171083-A1 | PHOTO-CURABLE COSMETIC COMPOSITIONS | L'OREAL S.A. (FR) | 2013-07-04 | — | — | US | disclosed |
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | disclosed |
| EP-0779553-B1 | Polyvinyl alcohol base photosensitive resin, photosensitive composition, and method for pattern formation using the same | TOYO GOSEI KOGYO KK (JP) | 2002-05-02 | — | — | EP | disclosed |
| WO-1996029312-A1 | STILBAZOLIUM SALT, AND PREPARATION AND USE THEREOF | ORION ELECTRIC CO., LTD. (KR) | 1996-09-26 | — | — | WO | disclosed |
| US-4564580-A | SAPONIFIED VINYL ACETATE POLYMER REACTED WITH STRYLPYRIDINIUM OR S | KOGYO GIJUTSUIN (JP) | 1986-01-14 | — | — | US | disclosed |
| EP-0130804-A2 | Photosensitive resin composition | KOGYO GIJUTSUIN (JP) | 1985-01-09 | — | — | EP | disclosed |
| US-4272620-A | Polyvinyl alcohol-styrylpyridinium photosensitive resins and method for manufacture thereof | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1981-06-09 | — | — | US | disclosed |
| US-4269941-A | CONFINING THE ENZYME IN A MATRIX BY EXPOSING TO LIGHT AN AQUEOUS SOLUTION OF ENZYME AND PHOTOSENSITIVE CROSSLINKABLE RESIN COMPRISING A PARTIALLY SAPONIFIED POLYVINYL ACETATE POLYMER MODIFIED BY AN A-P-FORMYLSTYRYL/PYRIDINIUM COMPOUND | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1981-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130171083-A1 | PHOTO-CURABLE COSMETIC COMPOSITIONS | KRT18, PLOD3, LCP1 | CYP2A6 3959/4885TERT 265/4885RAB9A 3462/4885 |
| US-20190091492-A1 | PHOTO-CURABLE COSMETIC COMPOSITIONS | KRT18, PLOD3, LCP1 | CYP2A6 3959/4885TERT 265/4885RAB9A 3462/4885 |
| US-20130167859-A1 | METHODS FOR MAKING UP A KERATINOUS SUBSTRATE | KRT18, DSG1, CUTA | CYP2A6 4254/4885TERT 73/4885RAB9A 3821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.