SCHEMBL5311344

SCHEMBL5311344

O=S(=O)(c1ccc(O)cc1)c1ccc(-c2ccc(S(=O)(=O)c3ccc(O)cc3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.59
PKM P14618 1/20 0.59
ESR1 P03372 2/20 0.58
ESR2 Q92731 1/20 0.58
LMNA P02545 1/20 0.56
CA2 P00918 4/20 0.54
CA12 O43570 2/20 0.54
CA9 Q16790 2/20 0.54
CA1 P00915 1/20 0.54
ENPP2 Q13822 1/20 0.54
RAPGEF4 Q8WZA2 1/20 0.50
UQCRB P14927 1/20 0.50
ELANE P08246 1/20 0.50
MMP3 P08254 1/20 0.48
BCL2L1 Q07817 1/20 0.48
SENP1 Q9P0U3 1/20 0.46
ALDH1A1 P00352 1/20 0.46
CYP3A4 P08684 1/20 0.46
MAPK1 P28482 1/20 0.46
ABL1 P00519 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3235446 1.00 GAA (0.59) GAAPKMESR1ESR2LMNA
SCHEMBL10395680 1.00 GAA (0.59) GAAPKMESR1ESR2LMNA
SCHEMBL811489 1.00 GAA (0.59) GAAPKMESR1ESR2LMNA
SCHEMBL811302 1.00 GAA (0.59) GAAPKMESR1ESR2LMNA
SCHEMBL18838 0.92 GAA (0.67) GAAPKMLMNACA2CA12
SCHEMBL3792342 0.92 GAA (0.67) GAAPKMLMNACA2CA12
SCHEMBL29724901 0.92 GAA (0.67) GAAPKMLMNACA2CA12
SCHEMBL124022 0.92 GAA (0.67) GAAPKMLMNACA2CA12
SCHEMBL7935388 0.91 HTR6 (0.61) GAAPKMESR1ESR2LMNA
SCHEMBL7929206 0.91 MMP3 (0.65) GAAPKMESR1LMNACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0195448-B1 PROCESS FOR PREPARING POLY (ARYL ETHER KETONE)S AMOCO CORPORATION (US) 1990-06-20 EP claimed
US-4638044-A Process for preparing poly(aryl ether ketone)s AMOCO CORPORATION (US) 1987-01-20 US claimed
EP-0195448-A2 Process for preparing poly (aryl ether ketone)s AMOCO CORPORATION (US) 1986-09-24 EP claimed
EP-2553011-B1 POLYMER COMPOSITIONS COMPRISING CORE/SHELL PARTICLES SOLVAY (BE) 2014-12-31 EP disclosed
US-8889824-B2 Grafted poly(arylsulfone) and a process for grafting a poly(arylsulfone) X-FLOW BV (NL) 2014-11-18 US disclosed
US-20140113093-A1 Polymers with reduced estrogenic activity SOLVAY SPECIALITY POLYMERS USA, LLC (US) 2014-04-24 US disclosed
US-20140113093-A1 Polymers with reduced estrogenic activity SOLVAY SPECIALITY POLYMERS USA, LLC (US) 2014-04-24 US disclosed
US-20130217839-A1 GRAFTED POLY(ARYLSULFONE) AND A PROCESS FOR GRAFTING A POLY(ARYLSULFONE) X-FLOW BV 2013-08-22 US disclosed
US-20130012634-A1 Polymer compositions comprising core/shell particles SOLVAY SA (BE) 2013-01-10 US disclosed
US-20130012634-A1 Polymer compositions comprising core/shell particles SOLVAY SA (BE) 2013-01-10 US disclosed
US-20130012634-A1 Polymer compositions comprising core/shell particles SOLVAY SA (BE) 2013-01-10 US disclosed
US-4774314-A POLYETHER KETONE POLYMERS AMOCO CORPORATION (US) 1988-09-27 US disclosed
EP-0275295-A1 BLENDS CONTAINING LIQUID CRYSTALLINE POLYESTERS AMOCO CORPORATION (US) 1988-07-27 EP disclosed
US-4748227-A Process for preparing poly(aryl ether)ketones using a sodium carbonate/organic acid salt catalyst AMOCO CORPORATION (US) 1988-05-31 US disclosed
WO-1988000605-A1 BLENDS CONTAINING LIQUID CRYSTALLINE POLYESTERS AMOCO CORPORATION (US) 1988-01-28 WO disclosed
EP-0213637-A2 Novel polyetherimides AMOCO CORPORATION (US) 1987-03-11 EP disclosed
EP-0211693-A1 Preparation of poly(aryl ether ketones) AMOCO CORPORATION (US) 1987-02-25 EP disclosed
US-4642327-A HIGH TEMPERATURE MOLDING MATERIALS AMOCO CORPORATION (US) 1987-02-10 US disclosed
US-4638044-A Process for preparing poly(aryl ether ketone)s AMOCO CORPORATION (US) 1987-01-20 US disclosed
EP-0195448-A2 Process for preparing poly (aryl ether ketone)s AMOCO CORPORATION (US) 1986-09-24 EP disclosed