SCHEMBL7929206

SCHEMBL7929206

O=S(=O)(c1ccc(O)cc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 3/20 0.65
BCL2L1 Q07817 1/20 0.65
UQCRB P14927 1/20 0.62
HTR6 P50406 1/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA9 Q16790 1/20 0.54
GAA P10253 4/20 0.52
PKM P14618 1/20 0.52
MMP2 P08253 3/20 0.50
MMP14 P50281 3/20 0.50
MMP1 P03956 2/20 0.50
MMP9 P14780 2/20 0.50
MMP8 P22894 2/20 0.50
MMP12 P39900 2/20 0.50
MMP13 P45452 2/20 0.50
MMP16 P51512 2/20 0.50
MEN1 O00255 2/20 0.50
MAPT P10636 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL4429619 0.98 MMP3 (0.61) MMP3BCL2L1UQCRBHTR6CA12
Biphenyl SCHEMBL28423762 0.96 HTR6 (0.61) MMP3BCL2L1UQCRBHTR6CA12
SCHEMBL7935388 0.96 HTR6 (0.61) MMP3BCL2L1UQCRBHTR6CA12
SCHEMBL10395680 0.91 GAA (0.59) MMP3BCL2L1UQCRBCA12CA1
SCHEMBL811489 0.91 GAA (0.59) MMP3BCL2L1UQCRBCA12CA1
SCHEMBL5311344 0.91 GAA (0.59) MMP3BCL2L1UQCRBCA12CA1
SCHEMBL811302 0.91 GAA (0.59) MMP3BCL2L1UQCRBCA12CA1
SCHEMBL3235446 0.91 GAA (0.59) MMP3BCL2L1UQCRBCA12CA1
SCHEMBL21155199 0.89 HTT (0.57) MMP3BCL2L1UQCRBCA12CA1
Phenol SCHEMBL6905378 0.89 HTR6 (0.62) UQCRBHTR6CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed
US-4868273-A SOLVENT RESISTANT POLYETHERS CONTAINING SULFONE AND CARBONYL GROUPS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-09-19 US disclosed