Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | DAGLA | Q9Y4D2 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30195971 | 0.85 | RXRA (0.64) | RXRANPC1RAB9ACOXFA4ALDH1A1 | |
| SCHEMBL3880185 | 0.85 | RXRA (0.64) | RXRANPC1RAB9ACOXFA4ALDH1A1 | |
| SCHEMBL5712102 | 0.85 | RXRA (0.55) | RXRACOXFA4ALDH1A1MAPTCYP2C19 | |
| SCHEMBL6210627 | 0.82 | RXRA (0.50) | RXRANPC1RAB9ACOXFA4MAPT | |
| SCHEMBL30026892 | 0.82 | RXRA (0.50) | RXRANPC1RAB9ACOXFA4MAPT | |
| SCHEMBL3782343 | 0.81 | COXFA4 (0.49) | RXRANPC1RAB9ACOXFA4MAPT | |
| SCHEMBL9870850 | 0.80 | CTNNB1 (0.48) | RXRACOXFA4DAGLACYP3A4CYP2D6 | |
| SCHEMBL14540851 | 0.80 | RXRA (0.44) | RXRAALDH1A1MAPTDAGLACYP3A4 | |
| SCHEMBL16742142 | 0.79 | COXFA4 (0.53) | RXRANPC1RAB9ACOXFA4NPSR1 | |
| SCHEMBL10563208 | 0.78 | TDP1 (0.44) | RXRANPC1RAB9ACOXFA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039609-A1 | PYRANODIBENZOFURAN DERIVATIVES WITH ANTIFUNGAL AND ANTIBACTERIAL ACTIVITY | INSTITUT PASTEUR (FR) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007039609-A1 | PYRANODIBENZOFURAN DERIVATIVES WITH ANTIFUNGAL AND ANTIBACTERIAL ACTIVITY | INSTITUT PASTEUR (FR) | 2007-04-12 | — | — | WO | disclosed |