Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP9 | P55211 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4000976 | 0.78 | MAOA (0.48) | MAOACES1BCHETDP2CASP3 | |
| SCHEMBL1818127 | 0.78 | MAOA (0.48) | MAOACES1BCHETDP2CASP3 | |
| SCHEMBL670717 | 0.78 | MAOA (0.48) | MAOACES1BCHETDP2CASP3 | |
| SCHEMBL1449448 | 0.78 | MAOA (0.48) | MAOACES1BCHETDP2CASP3 | |
| SCHEMBL7710688 | 0.77 | MAOA (0.44) | MAOACES1BCHETDP2CASP3 | |
| SCHEMBL7476251 | 0.75 | MAOA (0.45) | MAOACES1BCHETDP2CASP3 | |
| SCHEMBL5214053 | 0.73 | HTR2A (0.44) | MAOACES1BCHECASP3CASP6 | |
| SCHEMBL3931606 | 0.73 | SRD5A2 (0.45) | MAOACES1BCHETDP2CASP3 | |
| SCHEMBL7716195 | 0.73 | MAOA (0.44) | MAOACES1BCHETDP2CASP3 | |
| SCHEMBL6046310 | 0.73 | MAOA (0.44) | MAOACES1BCHETDP2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116574056-A | Preparation method of fluoroisoquinolone compound | 五邑大学 | 2023-08-11 | — | — | CN | claimed |
| CN-116574056-A | Preparation method of fluoroisoquinolone compound | 五邑大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-116574056-A | Preparation method of fluoroisoquinolone compound | 五邑大学 | 2023-08-11 | — | — | CN | disclosed |
| WO-2007053352-A2 | PYRROLOQUINOLINONE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2007-05-10 | — | — | WO | disclosed |
| US-20070099911-A1 | Pyrroloquinolinone derivatives as 5-hydroxytryptamine-6 ligands | WYETH (US) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099911-A1 | Pyrroloquinolinone derivatives as 5-hydroxytryptamine-6 ligands | HTR6, HTR5A, HTR2C | MAOA 182/4885CES1 2838/4885BCHE 1070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.