SCHEMBL5311575

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5311572	1.00	ATM (0.47)	ATMTSHRHPGDHCAR2ALDH1A1
	SCHEMBL12141976	1.00	ATM (0.47)	ATMTSHRHPGDHCAR2ALDH1A1
	SCHEMBL21457902	0.80	ATM (0.39)	ATMTSHRHPGDHCAR2ALDH1A1
	SCHEMBL21457901	0.80	ATM (0.39)	ATMTSHRHPGDHCAR2ALDH1A1
	SCHEMBL5316360	0.78	ALDH1A1 (0.32)	ALDH1A1LMNA
	SCHEMBL5310352	0.73	TSHR (0.50)	ATMTSHRALDH1A1CA2LMNA
	SCHEMBL5310349	0.73	TSHR (0.50)	ATMTSHRALDH1A1CA2LMNA
	SCHEMBL22558046	0.72	ATM (0.54)	ATMTSHRHPGDHCAR2ALDH1A1
	SCHEMBL5315401	0.72	TSHR (0.45)	ATMTSHRHPGDHCAR2ALDH1A1
	SCHEMBL14110792	0.71	ATM (0.30)	ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.