Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 4/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312539 | 0.90 | MEN1 (0.46) | EGLN1EGLN3MEN1KMT2ARXFP1 | |
| SCHEMBL5304912 | 0.82 | POLB (0.47) | EGLN1EGLN3MEN1KMT2ARXFP1 | |
| SCHEMBL5309462 | 0.79 | EGLN1 (0.46) | EGLN1EGLN3EGLN2MEN1KMT2A | |
| SCHEMBL5309258 | 0.79 | EGLN1 (0.49) | EGLN1EGLN3EGLN2TDP1TOP2A | |
| SCHEMBL5308669 | 0.76 | EGLN1 (0.43) | EGLN1EGLN3MEN1KMT2AKDM4E | |
| SCHEMBL5305537 | 0.76 | TDP1 (0.45) | EGLN1MEN1KMT2ARXFP1TDP1 | |
| SCHEMBL4431453 | 0.76 | EGLN1 (0.53) | EGLN1EGLN3EGLN2 | |
| SCHEMBL5312534 | 0.75 | EGLN1 (0.46) | EGLN1EGLN3EGLN2MEN1KMT2A | |
| SCHEMBL5312251 | 0.75 | MEN1 (0.48) | EGLN1EGLN3MEN1KMT2ARXFP1 | |
| SCHEMBL5312400 | 0.75 | MEN1 (0.48) | EGLN1EGLN3MEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | claimed |