Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309462 | 0.89 | EGLN1 (0.46) | EGLN1MEN1KMT2AEGLN3NR1H4 | |
| SCHEMBL5310529 | 0.80 | ROCK2 (0.39) | EGLN1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL5311709 | 0.76 | EGLN1 (0.43) | EGLN1MEN1KMT2AEGLN3TDP1 | |
| SCHEMBL5312534 | 0.73 | EGLN1 (0.46) | EGLN1MEN1KMT2AEGLN3HIF1A | |
| SCHEMBL5309258 | 0.71 | EGLN1 (0.49) | EGLN1EGLN3TDP1 | |
| SCHEMBL8244112 | 0.71 | EGLN1 (0.57) | EGLN1MEN1KMT2AEGLN3KDM4E | |
| SCHEMBL5308388 | 0.71 | THRA (0.48) | EGLN1MEN1KMT2AKDM4EHIF1A | |
| SCHEMBL15846253 | 0.70 | TDP1 (0.44) | EGLN1MEN1KMT2AEGLN3TDP1 | |
| SCHEMBL15846184 | 0.70 | SERPINE1 (0.46) | EGLN1MEN1KMT2AEGLN3TDP1 | |
| SCHEMBL5305537 | 0.69 | TDP1 (0.45) | EGLN1MEN1KMT2ATDP1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | claimed |