Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 14/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306749 | 0.88 | F10 (0.47) | SMN1; SMN2TDP1F10 | |
| SCHEMBL5310358 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2TDP1F10NPC1ALDH1A1 | |
| SCHEMBL5311766 | 0.83 | F10 (0.47) | SMN1; SMN2TDP1F10NPC1ALDH1A1 | |
| SCHEMBL5308836 | 0.80 | SCD (0.52) | SMN1; SMN2RAB9A | |
| SCHEMBL5313381 | 0.80 | SCD (0.41) | SMN1; SMN2NPC1ALDH1A1TSHRRAB9A | |
| SCHEMBL5311767 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2TDP1F10NPC1ALDH1A1 | |
| SCHEMBL5307037 | 0.77 | SCD (0.45) | NPC1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL5312567 | 0.77 | FAAH (0.37) | ALDH1A1 | |
| SCHEMBL5311207 | 0.76 | RAB9A (0.39) | SMN1; SMN2TDP1NPC1ALDH1A1PKM | |
| SCHEMBL5313442 | 0.76 | KCNQ3 (0.42) | SMN1; SMN2PKMRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |