Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL530471 | 0.85 | MAPT (0.56) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL529049 | 0.83 | MAPT (0.57) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL530943 | 0.80 | MAPT (0.57) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL529695 | 0.79 | MAPT (0.50) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL527915 | 0.78 | ALDH1A1 (0.59) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL528449 | 0.75 | ALDH1A1 (0.67) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL529111 | 0.73 | MAPT (0.64) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL528208 | 0.73 | ALDH1A1 (0.64) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL529488 | 0.72 | ALDH1A1 (0.63) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL528645 | 0.72 | ALDH1A1 (0.64) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |