Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH4 | P08319 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL531339 | 0.94 | TSHR (0.40) | TSHRMMP9ALDH1A1TDP1CYP3A4 | |
| SCHEMBL531179 | 0.71 | HSD17B10 (0.34) | TSHRMMP9ALDH1A1 | |
| SCHEMBL532319 | 0.69 | MMP9 (0.36) | LMNAMMP9ALDH1A1CYP3A4 | |
| SCHEMBL1902832 | 0.65 | LMNA (0.46) | TSHRLMNAPRSS1PRSS2PRSS3 | |
| SCHEMBL1905280 | 0.65 | LMNA (0.46) | TSHRLMNAPRSS1PRSS2PRSS3 | |
| SCHEMBL25172392 | 0.65 | LMNA (0.46) | TSHRLMNAPRSS1PRSS2PRSS3 | |
| SCHEMBL10703575 | 0.65 | LMNA (0.46) | TSHRLMNAPRSS1PRSS2PRSS3 | |
| SCHEMBL10875533 | 0.65 | LMNA (0.46) | TSHRLMNAPRSS1PRSS2PRSS3 | |
| SCHEMBL25171268 | 0.65 | LMNA (0.46) | TSHRLMNAPRSS1PRSS2PRSS3 | |
| SCHEMBL1901329 | 0.65 | LMNA (0.46) | TSHRLMNAPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414409-A1 | POLYMERS HAVING N-VINYL AMIDE AND HYDROXYL MOIETIES | Isp Investments Inc. (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010117660-A1 | POLYMERS HAVING N-VINYL AMIDE AND HYDROXYL MOIETIES | ISP INVESTMENTS INC. (US) | 2010-10-14 | — | — | WO | disclosed |