Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL531192 | 0.94 | TSHR (0.35) | TSHRALDH1A1TDP1CYP3A4MMP9 | |
| SCHEMBL10831507 | 0.71 | ADAMTS5 (0.37) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL9893490 | 0.70 | ALDH1A1 (0.45) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL3421951 | 0.64 | ALDH1A1 (0.46) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL2217145 | 0.63 | ALDH1A1 (0.50) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL3884493 | 0.62 | ALDH1A1 (0.68) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL387001 | 0.62 | — | — | |
| SCHEMBL21164464 | 0.62 | ALDH1A1 (0.59) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL21332621 | 0.61 | TSHR (0.50) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL1904090 | 0.61 | TSHR (0.56) | TSHRALDH1A1TDP1CYP3A4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414409-A1 | POLYMERS HAVING N-VINYL AMIDE AND HYDROXYL MOIETIES | Isp Investments Inc. (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010117660-A1 | POLYMERS HAVING N-VINYL AMIDE AND HYDROXYL MOIETIES | ISP INVESTMENTS INC. (US) | 2010-10-14 | — | — | WO | disclosed |