Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.40 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307496 | 0.86 | SCD (0.50) | MGLLHPGDS | |
| SCHEMBL5311619 | 0.83 | L3MBTL1 (0.49) | PRKAA2ALDH1A1SMN1; SMN2RAB9AHPGDS | |
| SCHEMBL5307018 | 0.80 | MEN1 (0.41) | TDP1EPHX2MEN1KMT2APRKAB2 | |
| SCHEMBL5312015 | 0.80 | KMT2A (0.49) | TDP1EPHX2MEN1KMT2APRKAB2 | |
| SCHEMBL5312492 | 0.76 | EGLN1 (0.42) | ALDH1A1MAPTHTTSMN1; SMN2NPSR1 | |
| SCHEMBL5309581 | 0.75 | SCD (0.44) | ALDH1A1MAPTHTTSMN1; SMN2NPSR1 | |
| SCHEMBL5307017 | 0.74 | MEN1 (0.44) | TDP1EPHX2MEN1KMT2APRKAB2 | |
| SCHEMBL5312057 | 0.73 | SCD (0.52) | MGLL | |
| SCHEMBL5307322 | 0.73 | SCD (0.54) | MGLLALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL5306427 | 0.73 | SCD (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |