Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | ITK | Q08881 | 4/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312732 | 0.90 | LCK (0.37) | RAB9AKDRLCKNPC1MEN1 | |
| SCHEMBL5312806 | 0.85 | LCK (0.39) | LCKMAPTNPC1PKMMEN1 | |
| SCHEMBL5312751 | 0.84 | KDR (0.44) | KDRLCK | |
| SCHEMBL5312953 | 0.83 | LCK (0.36) | KDRLCKIRAK4BRAF | |
| SCHEMBL5309710 | 0.83 | ALDH1A1 (0.37) | KDRLCKMAPTMEN1KMT2A | |
| SCHEMBL5310589 | 0.83 | LCK (0.38) | RAB9AKDRLCKMAPTNPC1 | |
| SCHEMBL5310123 | 0.83 | LCK (0.35) | KDRLCKMAPTIRAK4AURKB | |
| SCHEMBL5311529 | 0.83 | LCK (0.39) | RAB9AKDRLCKMAPTIRAK4 | |
| SCHEMBL14530871 | 0.83 | LCK (0.39) | KDRLCKMAPTMEN1KMT2A | |
| SCHEMBL5316887 | 0.82 | LCK (0.38) | KDRLCKMAPTIRAK4KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |