Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 6/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | ITK | Q08881 | 3/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312890 | 0.90 | LCK (0.38) | LCKKDRMEN1KMT2AIRAK4 | |
| SCHEMBL5312042 | 0.90 | HPGD (0.39) | LCKKDRMEN1KMT2AITK | |
| SCHEMBL5311529 | 0.88 | LCK (0.39) | LCKKDRIRAK4RAB9AALDH1A1 | |
| SCHEMBL14530871 | 0.88 | LCK (0.39) | LCKKDRMEN1KMT2ASYK | |
| SCHEMBL5311989 | 0.87 | LCK (0.37) | LCKKDRMEN1KMT2AIRAK4 | |
| SCHEMBL5312751 | 0.86 | KDR (0.44) | LCKKDR | |
| SCHEMBL5313272 | 0.85 | LCK (0.38) | LCKKDRMEN1KMT2ASYK | |
| SCHEMBL5312823 | 0.85 | LCK (0.35) | LCKKDRMEN1KMT2AIRAK4 | |
| SCHEMBL5312193 | 0.85 | ECE2 (0.42) | LCKKDRIRAK4 | |
| SCHEMBL5311490 | 0.84 | ITK (0.38) | LCKITKSYKBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |