Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313384 | 0.90 | SCD (0.40) | SCDEGLN1CYP2C9MAPK11MAPK14 | |
| SCHEMBL5312639 | 0.85 | SCD (0.38) | SCDEGLN1CYP2C9MAPK11MAPK14 | |
| SCHEMBL5310028 | 0.85 | EGLN1 (0.37) | SCDEGLN1CYP2C9MAPK11MAPK14 | |
| SCHEMBL5315122 | 0.84 | SCD (0.39) | SCDEGLN1CYP2C9MAPK11MAPK14 | |
| SCHEMBL5309303 | 0.80 | SCD (0.44) | SCDEGLN1CYP2C9MAPK11MAPK14 | |
| SCHEMBL5315119 | 0.79 | SCD (0.44) | SCDP2RX7HDAC3HDAC2HDAC1 | |
| SCHEMBL5311551 | 0.76 | PRKAA2 (0.43) | EGLN1 | |
| SCHEMBL5313381 | 0.75 | SCD (0.41) | SCDEGLN1CYP2C9MAPK11MAPK14 | |
| SCHEMBL5309835 | 0.75 | SCD (0.51) | SCDEGLN1 | |
| SCHEMBL5312612 | 0.74 | SCD (0.40) | SCDEGLN1MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |